BY FERRY
You can reach Astipalea by ferry from the port of Piraeus. There are every day routes connecting the island with the central port of Athens and with other Dodecanese islands (Rhodes, Kos, Kalymnos, Symi, Tilos, etc.). It is also connected to Cyclades islands (Paros, Naxos, Amorgos, etc.). The trip lasts about 12 hours.
For more information:
PORT AUTHORITIES OF PIRAEUS 210 4226000
PORT AUTHORITIES OF ASTIPALEA 22430 61208

BY PLANE
If you want to go by plane there are every day flights of Olympic Airways Athens – Astipalea and conversely. The trip lasts 1 hour.
For more information:
AIRPORT OF SPATA 210 353000
AIRPORT OF ASTIPALEA 22430 61410, 61665